First aid measures material safety data sheet material levofloxacin tablets 250 mg, 500 mg and 750 mg manufacturer lupin limited goa 403 722 india. Accidental release measures contain spill and collect, as appropriate. Source of sample, riedelde haen vetranal, sigmaaldrich inc. Hazards identification general advice consult a physician. Ofloxacin investigated as a drug, mutagen, and reproductive effector. Identification of the substancemixture and of the companyundertaking 1. Sds of ornidazole, safety data sheets, cas 16773425. Find patient medical information for ofloxacin oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
You should not use this medicine if you are allergic to ofloxacin or other fluoroquinolones ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, and others. If not breathing give artificial respiration in case of skin contact wash off with soap and plenty of water. Determination of the antibacterial ofloxacin in human urine and serum samples by solidphase spectrofluorimetry article in journal of pharmaceutical and biomedical analysis 304. Pdf determination of the antibacterial ofloxacin in.
It works by killing bacterial cells that cause infection. Ofloxacin is also sometimes used to treat other types of infection, including legionnaires disease type of lung infection, certain sexually transmitted diseases, infections of the bones and joints and of the stomach and intestines. Material safety data sheet of ofloxacin abmole bioscience. Pdf design and characterization of ofloxacin niosomes. Serious adverse reactions fluoroquinolones, including ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions e. If inhaled if breathed in, move person into fresh air. Only select registry of toxic effects of chemical substances rtecs data is presented here. Formulation and evaluation of ofloxacin aqueous injection. Ofloxacin c18h20fn3o4 cid 4583 structure, chemical names, physical and chemical. If swallowed, seek medical advice immediately and show the container or label.
Degenerative changes were observed in the tenocytes, and. Product monograph ofloxacin tablets 200, 300 and 400 mg therapeutic classification antibacterial agent actions and clinical pharmacology ofloxacin is a broadspectrum, synthetic fluoroquinolone antibacterial agent for oral administration. Pdf analysis of ofloxacin in plasma samples by high. Remove victim to fresh air and keep at rest in a position comfortable for breathing. It is a fluorinated carboxyquinolone antiinfective for topical ophthalmic use. Handling and storage handling wear personal protective equipmentface protection. Ofloxacin is a fluorinated 4quinolone which differs from other fluorinated 4quinolones in that there is a six member pyridobenzoxazine ring from positions 1 to 8 of the basic ring structure. In case of skin contact wash off with soap and plenty of water. The ofloxacin microspheres were prepared using natural polymers by nonionic crosslinking technique. Ofloxacin 2 mg infusion uses, dosage, side effects, price. Call a poison center or doctorphysician if you feel unwell.
Ofloxacin is thought to exert a bactericidal effect on susceptible bacterial cells by inhibiting the. The sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Serum, urine and tear concentrations of ofloxacin were measured in 30 healthy women at various time points. Determination of the antibacterial ofloxacin in human. A reverse phase high performance liquid chromatography method was developed for simultaneous estimation of nitazoxanide and ofloxacin in tablet formulation. Storage keep containers tightly closed in a dry, cool and wellventilated place. Sigmaaldrich offers a number of ofloxacin products. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only.
Ghs msds sds sheets for 10 normal sodium hydroxide solution in. View product specific information, msds, references and buying faq. Levofloxacin is a broadspectrum, thirdgeneration fluoroquinolone antibiotic and optically active lisomer of ofloxacin with antibacterial activity. Rphplc method for simultaneous estimation of nitazoxanide. If a person vomits place them in the recovery position so that vomit will not reenter the mouth and throat. Oct 15, 2012 this work presents the solid solubility in supercritical carbon dioxide scco 2 of two fluoroquinolonetype antibacterial drugs, namely norfloxacin and ofloxacin experimental data were obtained at 308. Ofloxacin 2 mg infusion is a broadspectrum antibiotic used to treat a variety of conditions such as bronchitis, pneumonia, and gonococcal infection. The achilles tendon specimens were examined by electron microscopy. A blood sample obtained 15 minutes after the completion of. Examples safety data sheet sds msds here you can see examples of safety data sheets in some of the various languages we handle. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting dna gyrase bacterial topoisomerase ii, an enzyme required for dna replication, rna transcription, and repair of. Ofloxacin cas 82419361 scbt santa cruz biotechnology. Empirical formula hill notation c 18 h 20 fn 3 o 4. Floxin ofloxacin side effects, images, uses, dosage.
The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Ofloxacin may also be used to treat or prevent anthrax or plague serious infections that may be spread on. In comparison with the vehicletreated controls, there were ultrastructural changes in all samples from the gemifloxacin, ofloxacin, and ciprofloxacintreated rats. The mean serum ofloxacin concentration ranged from 0. First aid measures if inhaled if breathed in, move person into fresh air. Ofloxacin is in a class of medications called quinolone antibiotics. This medicine is not recommended for use in cases of a common cold, flu, or other viral infections since it is active only against infections caused by bacteria.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. When taken by mouth or injection into a vein, these include pneumonia, cellulitis, urinary tract infections, prostatitis, plague, and certain types of infectious diarrhea. Show this safety data sheet to the doctor in attendance. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. Dec 21, 2018 what should i discuss with my healthcare provider before taking ofloxacin floxin. Download msds pdf search msds currently available for download bioworld offers enrofloxacin for your research at low price. Formulation and evaluation of ofloxacin aqueous injection 1, t. Material safety data sheet of ofloxacin contains identification of substance and details of the supplier of the safety data sheet. Ofloxacin functions by inhibiting dna gyrase, a topo ii topoisomerase ii and topo. Msds examples sds sheets msds authoring services inc. Floxin ofloxacin tablets tablets is a synthetic broadspectrum antimicrobial agent for oral administration. Chemically, ofloxacin has three condensed 6membered rings made up of a fluorinated carboxyquinolone with a benzoxazine ring. Ofloxacin united states pharmacopeia usp reference standard cas number 82419361. Ofloxacin ophthalmic solution ofloxacin ophthalmic solution.
See actual entry in rtecs for complete information. Determination of the antibacterial ofloxacin in human urine and serum samples by solidphase spectrofluorimetry. Design and characterization of ofloxacin niosomes article pdf available in pakistan journal of pharmaceutical sciences 266. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Sample globally harmonized system ghs compliant material safety data sheets.
Ofloxacin united states pharmacopeia usp reference standard. Chemical product and company identification product name. Ofloxacin or ciprofloxacin were used for comparison. We work hard to ensure that we are fully uptodate with regulations, and make sure to incorporate changes as soon as they occur, so that you do not risk having outofdate safety data sheets. If a person vomits place them in the recovery position so. Serum, urine and tear concentrations of ofloxacin were measured in 30 healthy women at various time points during a tenday course of treatment with ocuflox solution. Ofloxacin fluoroquinoloneantibiotic 82419361 sigmaaldrich. Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections. Ofloxacin cas 82419361 msds by bluenesslittle issuu. Analysis of ofloxacin in plasma samples by highperformance liquid chromatography article pdf available in chromatographia 557. College of pharmacy, chitradurga, karnataka india abstract ofloxacin is a synthetic fluoroquinolone broad spectrum anti microbial agent used in the treatment of bacterial.
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